These photostats are selections from the original manuscript, which is a portion of a volume entitled "Letters, facts, and observations upon a variety of subjects." The topics include medicine, slavery, the African church, gossip and social events, the deaths of prominent Philadelphians, and Rush's philosophy on various subjects. Contains questions for Alexander McGillivray, on diseases, mortality, passions of Creek Indians.

This item contains entries about prominent people (primarily accounts of their deaths); Philadelphia events and gossip; the Pennsylvania Hospital; questions for Meriwether Lewis on Indian physical history, medicine, morals, and religion; and his views on marriage, religion, physicians, etc. Also includes meeting with Captain Wells and Little Turtle; speculations on Indian skin color at the equator.

These photostats of letters were collected from various repositories by Lyman H. Butterfield for his book, "Letters of Benjamin Rush" 2 v. American Philosophical Society Memoirs 30(1951). Some of the topics discussed are Philadelphia and United States politics, slavery, Afro-American churches, and medicine.